WB, IP
H, R, M
68KD
IgG1
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Store at -20°C. Do not aliquot the antibody.
WB: 1:2,000-5,000 IP:1:200
The Lamin B1 antibody can detects endogenous Lamin B1 protein.
ADLD, LMB1,LMNB1, MGC111419, OTTHUMP00000159218
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family
of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled
as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and
gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.
1.W Q ,Y H ,Z B , et al.Lipopolysaccharide-induced DNA damage response activates nuclear factor κB signalling pathway via GATA4 in dental pulp cells.[J].International endodontic journal,2019,52(12):1704-1715.(IF 3.331)
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